Edema During Pregnancy : Causes, Symptoms, Diagnosis & Treatment

Last Updated: 02/09/2022

Edema during pregnancy can be physiological or pathological. Observed with preeclampsia, compression of large vessels by the uterus, diseases of the kidneys, heart and blood vessels, some hypovitaminosis, endocrine diseases. They are more often detected in the distal extremities, especially the lower ones. Less commonly found on the face or spread throughout the body. They are diagnosed on the basis of an external examination, special calculations. The cause is established using hardware techniques, laboratory tests. Treatment includes diet, diuretics, antispasmodics, antihypertensives, antiplatelet agents, and other drugs. The birth plan is determined individually.

general characteristics

Edema during pregnancy can be detected both in normal conditions and in the development of various pathological conditions. The tendency to swelling during this period is due to an increase in the level of progesterone, an increase in the amount of fluid in the body. In pregnant women, compared with non-pregnant women, the volume of fluid increases by 6-8 liters, 4-6 of which are contained in the placenta, amniotic fluid, fetus, and the remaining 2-4 are distributed throughout the body.

Why does swelling occur during pregnancy

Physiological causes

The causes of this manifestation during pregnancy are:

Patients of small stature tend to develop edema. The predisposing factor is excess weight. In girls with a slight excess of body weight, pastosity appears more often, but does not reach a significant degree of severity. In patients with severe obesity, the tendency to peripheral edema increases, the symptom becomes permanent, combined with shortness of breath, pain in the spine, joints of the legs.

Gestosis

Puffiness is characteristic of all late toxicoses, which, in essence, are successive stages of one pathological process. The change of stages can be both gradual and lightning fast, which makes it important to take into account the severity of the symptom, other manifestations to determine the severity of the condition, the need for urgent measures. The following variants of gestosis are possible:

  • Dropsy of pregnancy. It develops due to violations of the water-electrolyte balance, increased vascular permeability, fluid release into the tissues. Initially, the swelling is insignificant, covering only the limbs, then the swelling becomes generalized. A characteristic external sign is a glossy skin tone. The patient is thirsty. There is a decrease in urination.
  • Nephropathy. Replaces dropsy in 25% of women. Manifested by edema, proteinuria, increased blood pressure. Puffiness varies from slight pastosity of the face, hands to generalized edema. Progressive hypertension is accompanied by headaches, nausea, and vomiting. Other typical symptoms of nephropathy are weakness, dizziness, thirst, shortness of breath, dyspepsia, and back pain.
  • Preeclampsia. Formed after nephropathy. Edema persists. The above signs are supplemented by heaviness in the back of the head, intense cephalalgia, fatigue, lethargy, lethargy, tremors, sweating of the hands, insomnia or increased drowsiness. A quarter of patients have visual disturbances. Pain in the epigastric region, nausea, vomiting are possible.
  • Eclampsia. Replaces preeclampsia over a period not exceeding 3-4 days. Against the background of swelling of the trunk and limbs, other symptoms of preeclampsia, a convulsive seizure occurs, followed by a coma, which turns into a recovery of consciousness or worsens.

inferior vena cava syndrome

As a rule, it is diagnosed after the 25th week of pregnancy. Manifested by tachycardia, weakness, shortness of breath, increased fetal movement in the supine position. Cardialgia, fear, anxiety, visual disturbances, noise and ringing in the ears are detected. Postural hypotension develops, sometimes fainting. Edema in the IVC syndrome is found on the lower extremities, due to the deterioration of the outflow of blood against the background of compression of a large venous trunk.

Renal pathologies

An increased likelihood of edema during pregnancy is noted in women with a single kidney due to organ agenesis or after nephrectomy. An increase in the load on the urinary system can lead to morning swelling of the face, a decrease or increase in urination, the appearance of blood impurities, and cloudy urine. The general condition worsens, drowsiness, weakness, fatigue are observed. There is a high probability of developing gestational pyelonephritis, which is manifested by dysuria, severe pain similar to renal colic.

Glomerulonephritis occurs against the background of infections, toxic effects, systemic pathologies. In the acute form of the disease, the face and eyelids suddenly become swollen, weakness, hyperthermia, chills, appetite disorders, and back pain are observed. Urination decreases, urine becomes brown, red or pink.

In more than half of the patients, glomerulonephritis during pregnancy is chronic. Edema syndrome is pronounced in 5% of patients. It may involve the face, hands, feet. In severe cases, swelling spreads to the whole body, anasarca develops. The presence of ascites is indicated by a rapid increase in the abdomen. Increasing shortness of breath is a sign of hydrothorax.

Varicose disease

In 60-80% of cases, varicose veins are provoked by pregnancy, in other women it is aggravated due to the increased load on the vessels. It usually affects the lower extremities. At the initial stage, a slight pastiness occurs in the evening, especially after prolonged standing, combined with a feeling of heaviness, a “buzz” in the legs. Subsequently, pain, local convulsions appear. Severe swelling of the feet, ankles, lower legs indicates damage to the deep veins.

A rare variant of the disease is genital varicose veins. Possible swelling of the labia and perineum, blood smearing after sexual intercourse, itching, heaviness, bursting in the genital area. There are aching and pulling pains in the lower abdomen and genitals, radiating to the groin, sacrum, lower back.

Thrombophilia

The pathological condition is caused by disorders of the blood coagulation system, accompanied by the formation of blood clots. The most common complication of thrombophilia during pregnancy is thrombophlebitis. Swelling of the leg with deep venous thrombosis is combined with arching pains, cyanosis of the skin, swelling of the superficial veins, an increase in local temperature, thickening, and soreness of the damaged vessel. Due to thrombosis of the vessels of the placenta, severe preeclampsia develops with massive edema of the abdomen, upper and lower extremities.

Arterial hypertension

In two-thirds of women, it is provoked by pregnancy, after the birth of a child, blood pressure returns to normal. There is an increased tendency to edema of the distal legs. Possible swelling of the hands. The main manifestations of hypertension during pregnancy are dizziness, tinnitus, headaches, fatigue, shortness of breath, tachycardia.

Heart diseases

The main cardiac cause of edema during pregnancy is considered to be circulatory failure in rheumatic or congenital heart defects. The lower extremities swell mainly: shins, feet, ankle joints. Drowsiness, muscle weakness, fatigue, interruptions in the work of the heart, shortness of breath, a bluish tint or pallor of the skin are observed. A more rare cardiac pathology that provokes the development of edema is dilated cardiomyopathy.

Pathology of the thyroid gland

Quite common in pregnant women, iodine deficiency causes edema only when the level of thyroid hormones decreases. In severe cases, clinically pronounced hypothyroidism develops. The most noticeable edema is observed on the face and neck, sometimes covering the entire body. The face is mask-like, puffy. There are no skin color changes or pressure marks. Rapid weight gain, lethargy, constipation, nausea, deterioration of hair and nails are found.

Hypovitaminosis

Edema, convulsions, lethargy, early toxicosis are observed in pregnant women with hypovitaminosis B6. These symptoms are exacerbated by concomitant deficiency of vitamins B9 and B12. The development of a specific clinical picture is preceded by apathy, weakness, drowsiness, loss of appetite, deterioration in concentration, and a tendency to colds.

Diagnostics

The obstetrician-gynecologist is engaged in determining the cause of the symptom during pregnancy. According to the indications, the patient is referred for consultations to a nephrologist, phlebologist, cardiologist, and other specialists. The survey is carried out using the following methods:

  • Collection of anamnesis. The doctor interrogates the patient, revealing clinical signs of puffiness. Swelling of the legs is indicated by the feeling that the usual shoes have become tight, the inability to fasten the boots, pronounced, long-lasting marks from the rubber bands of the socks on the skin. Hand swelling is indicated by problems when removing and putting on rings.
  • Physical examination. The specialist determines the prevalence of edema, establishes manifestations that indicate the etiology of the symptom. Detects external and palpatory signs of ascites and anasarca, listens to the heart and lungs to detect defects, hydrothorax.
  • Special measurements. Indicated for suspected presence of latent edema. Based on the determination of daily weight gain, calculation of diuresis. Normally, the weekly increase in body weight is less than 30 g, the daily volume of fluid drunk exceeds the amount of urine by no more than 20-25%. The deviation of these indicators indicates a high probability of swelling.
  • hardware methods. Safe, sufficiently informative ultrasound and electrophysiological studies are recommended. Gynecological ultrasound, dopplerography of uteroplacental blood flow are performed. For pathologies of the urinary system, ultrasound of the kidneys is prescribed, for hypothyroidism - ultrasound of the thyroid gland, for varicose veins and thrombophlebitis - ultrasound of the lower extremities. Cardiological patients along with echocardiography produce ECG, daily, phonocardiography.
  • Laboratory tests. In case of kidney diseases, general and biochemical urine tests are indicated, and in case of hypothyroidism, hormone tests are indicated. To determine the presence and type of thrombophilia, special studies are carried out. Laboratory examination for gestosis includes KLA, OAM, biochemical blood and urine tests, coagulogram.

Treatment

Conservative therapy

Depending on the cause of the symptom, the following therapeutic measures are carried out:

  • Gestosis. Patients are hospitalized (except in cases of mild dropsy). Assign bed rest. The correction of the drinking regimen, a special diet with an increased amount of protein, salt restriction are shown. Diuretics are not recommended, as they can aggravate the release of vascular fluid into the tissues and contribute to the growth of edema. Apply antispasmodics, desensitizing, hypotensive, sedative and anticonvulsants, infusion therapy, oxygen therapy.
  • Diseases of the kidneys. Prescribe a special diet. In mild cases, herbal remedies are used. In clinically significant forms of glomerulonephritis, the treatment regimen includes loop diuretics, xanthines, potassium-containing agents, antihypertensive drugs, antiplatelet agents. A solitary kidney may require hormones and antibiotics. Iron supplements are needed to increase hemoglobin levels. Effective pulsed ultrasound on the lumbar region.
  • Varicose veins. Carry out compression therapy, treatment with phlebotonics and phleboprotectors, anticoagulants, antiaggregants. Moderate physical activity, lymphatic drainage massage, physiotherapy exercises, a diet with a lot of vegetable fats and fiber are useful.
  • thrombophilia. Patients with thrombosis are prescribed anticoagulants and thrombolytics. In case of violations of blood rheology, antiplatelet agents are used prophylactically. Carry out hemodilution (erythrocytopheresis, thrombocytopheresis), hirudotherapy. With a lack of clotting factors and anticoagulants, fresh or fresh frozen plasma is transfused. Sometimes plasmapheresis is needed.
  • Arterial hypertension. As part of antihypertensive therapy, alpha-2-agonists, selective beta-blockers, myotropic vasodilators, slow calcium channel blockers are prescribed. To improve microcirculation and metabolic processes in the fetoplacental system, peripheral vasodilators are used. Diuretics and ACE blockers are not recommended for pregnant women with hypertension.
  • Damage to the thyroid gland. The basis of treatment is hormonal and iodine-containing drugs. In case of organ disorders due to hypothyroxinemia, cardioprotectors, antiarrhythmic drugs, immunostimulants, vitamin-mineral complexes, nootropics are additionally used.
  • Heart defects. Therapy includes antibiotics, nitrates, beta-blockers, cardiac glycosides, anticoagulants, loop and thiazide diuretics. Treatment regimens are compiled individually, taking into account the characteristics of the pathology, the severity of symptoms, and the duration of pregnancy.

Surgery

Natural childbirth is usually the preferred option. If necessary, a caesarean section, small obstetric operations are performed. Sometimes early delivery is required. Specific surgical treatment, if possible, is postponed until the end of pregnancy or lactation. Patients with varicose veins, according to indications, undergo crossectomy, miniphlebectomy, endovasal laser coagulation. Minimally invasive methods of treating heart defects are closed mitral commissurotomy, balloon dilatation of aortic stenosis.