Pain in the perineum in men is observed with inflammatory diseases of the genital organs, STIs, non-specific infectious processes, volumetric formations, pelvic congestion. It can be found in coccygodynia, proctological and urological pathologies. The cause of the symptom is established by the results of a survey, rectal examination, ultrasound, laboratory tests. Treatment includes antibiotics, immunomodulators, antispasmodics, NSAIDs, hormones, anticoagulants, physiotherapy, prostate massage, surgical techniques.