Pain in the lower jaw is observed with periostitis, osteomyelitis, maxillary abscess, fractures, tumors. It is provoked by some dental pathologies, bruxism, neuralgia, coronary artery disease. It can be constant, intermittent, strong, non-intense, dull, sharp, pressing, aching, bursting, twitching. The cause is determined based on the results of the survey, general and dental examination, imaging, electrophysiological, laboratory techniques. Therapy includes analgesics, antibiotics, glucocorticoids, and other medications. Sometimes operations are performed.