Hyperfibrinogenemia is a pathological condition characterized by an increase in the concentration of fibrinogen in the blood over 4 g/l. In addition to its important role in blood coagulation, fibrinogen is one of the major acute phase proteins. Therefore, any kind of cellular or tissue damage or inflammation is accompanied by an increase in the production of this protein. The cause of hyperfibrinogenemia can be acute infections, injuries, burns, etc. The level of fibrinogen is examined in blood plasma as part of a standard coagulogram. Correction is carried out by treating the underlying disease.