Pain in the heart occurs due to cardiac and non-cardiac causes. The most common pathologies accompanied by pain syndrome: angina pectoris, arterial hypertension, arrhythmias. The symptom is characteristic of myocarditis and pericarditis, rheumatism, cardiomyopathy. Extracardiac factors - cardioneurosis, osteochondrosis, GERD, etc. For diagnosis, instrumental techniques are performed (ECG, echocardiography, coronary angiography), laboratory tests (lipid profile, assessment of acute phase parameters, study of markers of myocardial necrosis). To stop pain in the heart, treatment of the underlying disease is necessary.